| Reaction Details |
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 | Report a problem with these data |
| Target | Chitinase |
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| Ligand | BDBM50347554 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_756521 (CHEMBL1804594) |
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| IC50 | 1600±n/a nM |
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| Citation |  Garner, AL; Gloeckner, C; Tricoche, N; Zakhari, JS; Samje, M; Cho-Ngwa, F; Lustigman, S; Janda, KD Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus. J Med Chem54:3963-72 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chitinase |
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| Name: | Chitinase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55694.80 |
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| Organism: | Onchocerca volvulus |
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| Description: | ChEMBL_1369100 |
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| Residue: | 497 |
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| Sequence: | MRIGAMLIPFIILGNAIIAYGYVRGCYYTNWAQYRQGEGKFLPEDIPKGLCTHILYAFAK
VDQSGTSLPFEWNDEDTNWSKGMYSRVTKLKENDPEMKILLSYGGYNFGSSTFTAIRNRA
EKRKHFIKSAIAFLRKNKFDGFDFDWEYPIGMAQEYAKLVNEMKVAFVEEAKKSDSEQLL
LTAAVSAGKHTIDQSYNVQSLGENFDLLSLMSYDFHGSWEMNVDLHAKLHPTKGETSGTG
IFNTEFAANYWLSKGMPKQKIIIGIPTYGRGWTLRDSSKTTIGAEGISPSSPSTTNPAGG
TAAYWEICKYLKEGGKETIDEQGVGACMVQGSQWYGYDNEETIRMKMRWLKEKGYGGAFI
WTLDFDDFKGTSCGEGPYPLLSAINHELKGEATATTRSLRTTITQSSTIGSTKFETTTTA
SEITKNNKIKTTTIAVEPTGESSDIKCPESFGLFRHPNDCHLFIHCAHDHPYVKLCPPNT
FFNDKIKVCDHFGECDE
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| BDBM50347554 |
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| n/a |
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| Name | BDBM50347554 |
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| Synonyms: | CHEMBL1801795 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15I2NO2 |
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| Mol. Mass. | 507.1047 |
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| SMILES | CC(C)c1ccc(NC(=O)c2cc(I)cc(I)c2O)cc1 |
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| Structure | 
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