| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50213115 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_755355 (CHEMBL1804511) |
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| EC50 | 13±n/a nM |
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| Citation |  Jozwiak, K; Woo, AY; Tanga, MJ; Toll, L; Jimenez, L; Kozocas, JA; Plazinska, A; Xiao, RP; Wainer, IW Comparative molecular field analysis of fenoterol derivatives: A platform towards highly selective and effective beta(2)-adrenergic receptor agonists. Bioorg Med Chem18:728-36 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50213115 |
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| n/a |
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| Name | BDBM50213115 |
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| Synonyms: | (R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)ethylamino]ethyl}-1,3-benzenediol | CHEMBL229401 | US10617654, Compound (R,R)-5 | US9492405, (R,R)-5 | US9492405, 39 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23NO3 |
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| Mol. Mass. | 337.4122 |
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| SMILES | C[C@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1 |
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| Structure | 
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