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Compile Data Set for Download or QSAR

Found 223 hits with Last Name = 'woo' and Initial = 'ay'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM25771
PNG
(1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-ph...)
Show SMILES OCc1cc(ccc1O)C(O)CNCCCCCCOCCCCc1ccccc1
Show InChI InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2
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1.5n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [125I]-CYP from human beta2-adrenergic receptor expressed in COS-7 cells by gamma counting


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50569866
PNG
(CHEMBL4860571)
Show SMILES O[C@H]1[C@@H](CCc2c(O)c(O)ccc12)NCC1CC(F)(F)C1 |r|
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25n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to beta2 adrenoceptor (unknown origin)


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01195
BindingDB Entry DOI: 10.7270/Q24F1VJ7
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50569864
PNG
(CHEMBL4869517)
Show SMILES O[C@H]1[C@@H](CCc2c(O)c(O)ccc12)NC1CCCC1 |r|
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25n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to beta2 adrenoceptor (unknown origin)


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01195
BindingDB Entry DOI: 10.7270/Q24F1VJ7
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50000504
PNG
(6-Isopropylamino-5,6,7,8-tetrahydro-naphthalene-1,...)
Show SMILES CC(C)N[C@@H]1CCc2c(O)c(O)ccc2[C@H]1O
Show InChI InChI=1S/C13H19NO3/c1-7(2)14-10-5-3-9-8(12(10)16)4-6-11(15)13(9)17/h4,6-7,10,12,14-17H,3,5H2,1-2H3/t10-,12-/m1/s1
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32n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to beta2 adrenoceptor (unknown origin)


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01195
BindingDB Entry DOI: 10.7270/Q24F1VJ7
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50569865
PNG
(CHEMBL4871979)
Show SMILES O[C@H]1[C@@H](CCc2c(O)c(O)ccc12)NCCCF |r|
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97n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to beta2 adrenoceptor (unknown origin)


Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01195
BindingDB Entry DOI: 10.7270/Q24F1VJ7
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348432
PNG
(CHEMBL1800935)
Show SMILES OCc1cc(ccc1O)C(O)CNCCCCCCCCCCCc1ccccc1
Show InChI InChI=1S/C26H39NO3/c28-21-24-19-23(16-17-25(24)29)26(30)20-27-18-12-7-5-3-1-2-4-6-9-13-22-14-10-8-11-15-22/h8,10-11,14-17,19,26-30H,1-7,9,12-13,18,20-21H2
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220n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [125I]-CYP from human beta2-adrenergic receptor expressed in COS-7 cells by gamma counting


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348430
PNG
(CHEMBL1800963 | US9492405, 44)
Show SMILES COc1ccc(C[C@@H](C)NC[C@H](O)c2cc(O)cc(O)c2)c2ccccc12 |r|
Show InChI InChI=1S/C22H25NO4/c1-14(23-13-21(26)16-10-17(24)12-18(25)11-16)9-15-7-8-22(27-2)20-6-4-3-5-19(15)20/h3-8,10-12,14,21,23-26H,9,13H2,1-2H3/t14-,21+/m1/s1
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280n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from human beta2-adrenergic receptor expressed in HEK 293 cells


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348431
PNG
(CHEMBL1800934 | US9492405, 45)
Show SMILES COc1ccc(C[C@H](C)NC[C@H](O)c2cc(O)cc(O)c2)c2ccccc12 |r|
Show InChI InChI=1S/C22H25NO4/c1-14(23-13-21(26)16-10-17(24)12-18(25)11-16)9-15-7-8-22(27-2)20-6-4-3-5-19(15)20/h3-8,10-12,14,21,23-26H,9,13H2,1-2H3/t14-,21-/m0/s1
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320n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from human beta2-adrenergic receptor expressed in HEK 293 cells


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348428
PNG
(CHEMBL1800961 | US9492405, 40)
Show SMILES C[C@H](Cc1ccc2ccccc2c1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C21H23NO3/c1-14(8-15-6-7-16-4-2-3-5-17(16)9-15)22-13-21(25)18-10-19(23)12-20(24)11-18/h2-7,9-12,14,21-25H,8,13H2,1H3/t14-,21+/m1/s1
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410n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from human beta2-adrenergic receptor expressed in HEK 293 cells


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348429
PNG
(CHEMBL1800962 | US9492405, 41)
Show SMILES C[C@@H](Cc1ccc2ccccc2c1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C21H23NO3/c1-14(8-15-6-7-16-4-2-3-5-17(16)9-15)22-13-21(25)18-10-19(23)12-20(24)11-18/h2-7,9-12,14,21-25H,8,13H2,1H3/t14-,21-/m0/s1
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510n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from human beta2-adrenergic receptor expressed in HEK 293 cells


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348426
PNG
(CHEMBL1800936 | US9492405, 48)
Show SMILES CC[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C18H23NO4/c1-2-14(7-12-3-5-15(20)6-4-12)19-11-18(23)13-8-16(21)10-17(22)9-13/h3-6,8-10,14,18-23H,2,7,11H2,1H3/t14-,18+/m1/s1
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1.27E+3n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from human beta2-adrenergic receptor expressed in HEK 293 cells


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM25771
PNG
(1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-ph...)
Show SMILES OCc1cc(ccc1O)C(O)CNCCCCCCOCCCCc1ccccc1
Show InChI InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2
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2.30E+3n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [125I]-CYP from human beta1-adrenergic receptor expressed in COS-7 cells by gamma counting


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Homo sapiens (Human))
BDBM50348432
PNG
(CHEMBL1800935)
Show SMILES OCc1cc(ccc1O)C(O)CNCCCCCCCCCCCc1ccccc1
Show InChI InChI=1S/C26H39NO3/c28-21-24-19-23(16-17-25(24)29)26(30)20-27-18-12-7-5-3-1-2-4-6-9-13-22-14-10-8-11-15-22/h8,10-11,14-17,19,26-30H,1-7,9,12-13,18,20-21H2
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2.30E+3n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [125I]-CYP from human beta1-adrenergic receptor expressed in COS-7 cells by gamma counting


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348427
PNG
(CHEMBL1800960 | US9492405, 49)
Show SMILES CC[C@@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C18H23NO4/c1-2-14(7-12-3-5-15(20)6-4-12)19-11-18(23)13-8-16(21)10-17(22)9-13/h3-6,8-10,14,18-23H,2,7,11H2,1H3/t14-,18-/m0/s1
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5.76E+3n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from human beta2-adrenergic receptor expressed in HEK 293 cells


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50348431
PNG
(CHEMBL1800934 | US9492405, 45)
Show SMILES COc1ccc(C[C@H](C)NC[C@H](O)c2cc(O)cc(O)c2)c2ccccc12 |r|
Show InChI InChI=1S/C22H25NO4/c1-14(23-13-21(26)16-10-17(24)12-18(25)11-16)9-15-7-8-22(27-2)20-6-4-3-5-19(15)20/h3-8,10-12,14,21,23-26H,9,13H2,1-2H3/t14-,21-/m0/s1
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1.48E+4n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from beta1-adrenergic receptor in Sprague-Dawley rat cortical membrane after 2 hrs


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50348428
PNG
(CHEMBL1800961 | US9492405, 40)
Show SMILES C[C@H](Cc1ccc2ccccc2c1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C21H23NO3/c1-14(8-15-6-7-16-4-2-3-5-17(16)9-15)22-13-21(25)18-10-19(23)12-20(24)11-18/h2-7,9-12,14,21-25H,8,13H2,1H3/t14-,21+/m1/s1
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1.66E+4n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from beta1-adrenergic receptor in Sprague-Dawley rat cortical membrane after 2 hrs


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50348429
PNG
(CHEMBL1800962 | US9492405, 41)
Show SMILES C[C@@H](Cc1ccc2ccccc2c1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C21H23NO3/c1-14(8-15-6-7-16-4-2-3-5-17(16)9-15)22-13-21(25)18-10-19(23)12-20(24)11-18/h2-7,9-12,14,21-25H,8,13H2,1H3/t14-,21-/m0/s1
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2.71E+4n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from beta1-adrenergic receptor in Sprague-Dawley rat cortical membrane after 2 hrs


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50348427
PNG
(CHEMBL1800960 | US9492405, 49)
Show SMILES CC[C@@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C18H23NO4/c1-2-14(7-12-3-5-15(20)6-4-12)19-11-18(23)13-8-16(21)10-17(22)9-13/h3-6,8-10,14,18-23H,2,7,11H2,1H3/t14-,18-/m0/s1
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1.17E+5n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from beta1-adrenergic receptor in Sprague-Dawley rat cortical membrane after 2 hrs


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50348430
PNG
(CHEMBL1800963 | US9492405, 44)
Show SMILES COc1ccc(C[C@@H](C)NC[C@H](O)c2cc(O)cc(O)c2)c2ccccc12 |r|
Show InChI InChI=1S/C22H25NO4/c1-14(23-13-21(26)16-10-17(24)12-18(25)11-16)9-15-7-8-22(27-2)20-6-4-3-5-19(15)20/h3-8,10-12,14,21,23-26H,9,13H2,1-2H3/t14-,21+/m1/s1
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1.61E+5n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from beta1-adrenergic receptor in Sprague-Dawley rat cortical membrane after 2 hrs


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-1 adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50348426
PNG
(CHEMBL1800936 | US9492405, 48)
Show SMILES CC[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C18H23NO4/c1-2-14(7-12-3-5-15(20)6-4-12)19-11-18(23)13-8-16(21)10-17(22)9-13/h3-6,8-10,14,18-23H,2,7,11H2,1H3/t14-,18+/m1/s1
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4.24E+5n/an/an/an/an/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Displacement of [3H]CGP-12177 from beta1-adrenergic receptor in Sprague-Dawley rat cortical membrane after 2 hrs


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348427
PNG
(CHEMBL1800960 | US9492405, 49)
Show SMILES CC[C@@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C18H23NO4/c1-2-14(7-12-3-5-15(20)6-4-12)19-11-18(23)13-8-16(21)10-17(22)9-13/h3-6,8-10,14,18-23H,2,7,11H2,1H3/t14-,18-/m0/s1
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n/an/an/an/a 17n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348428
PNG
(CHEMBL1800961 | US9492405, 40)
Show SMILES C[C@H](Cc1ccc2ccccc2c1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C21H23NO3/c1-14(8-15-6-7-16-4-2-3-5-17(16)9-15)22-13-21(25)18-10-19(23)12-20(24)11-18/h2-7,9-12,14,21-25H,8,13H2,1H3/t14-,21+/m1/s1
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n/an/an/an/a 0.400n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213115
PNG
((R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21+/m1/s1
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n/an/an/an/a 13n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213099
PNG
((R,R)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Show SMILES COc1ccc(C[C@@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1
Show InChI InChI=1S/C18H23NO4/c1-12(7-13-3-5-17(23-2)6-4-13)19-11-18(22)14-8-15(20)10-16(21)9-14/h3-6,8-10,12,18-22H,7,11H2,1-2H3/t12-,18+/m1/s1
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n/an/an/an/a 0.300n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213110
PNG
((R,S)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21-/m0/s1
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n/an/an/an/a 2.70n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213106
PNG
((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Show SMILES C[C@@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17-/m0/s1
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n/an/an/an/a 4.70n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348426
PNG
(CHEMBL1800936 | US9492405, 48)
Show SMILES CC[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C18H23NO4/c1-2-14(7-12-3-5-15(20)6-4-12)19-11-18(23)13-8-16(21)10-17(22)9-13/h3-6,8-10,14,18-23H,2,7,11H2,1H3/t14-,18+/m1/s1
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n/an/an/an/a 2.80n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213098
PNG
((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
Show SMILES C[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17+/m1/s1
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n/an/an/an/a 0.300n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213097
PNG
((S,R)-(+)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Show SMILES COc1ccc(C[C@@H](C)NC[C@@H](O)c2cc(O)cc(O)c2)cc1
Show InChI InChI=1S/C18H23NO4/c1-12(7-13-3-5-17(23-2)6-4-13)19-11-18(22)14-8-15(20)10-16(21)9-14/h3-6,8-10,12,18-22H,7,11H2,1-2H3/t12-,18-/m1/s1
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n/an/an/an/a 7.20n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348431
PNG
(CHEMBL1800934 | US9492405, 45)
Show SMILES COc1ccc(C[C@H](C)NC[C@H](O)c2cc(O)cc(O)c2)c2ccccc12 |r|
Show InChI InChI=1S/C22H25NO4/c1-14(23-13-21(26)16-10-17(24)12-18(25)11-16)9-15-7-8-22(27-2)20-6-4-3-5-19(15)20/h3-8,10-12,14,21,23-26H,9,13H2,1-2H3/t14-,21-/m0/s1
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n/an/an/an/a 4n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213103
PNG
((S,R)-(+)-fenoterol | CHEMBL229477 | US10617654, C...)
Show SMILES C[C@H](Cc1ccc(O)cc1)NC[C@@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17-/m1/s1
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n/an/an/an/a 8.5n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50213120
PNG
((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Show SMILES COc1ccc(C[C@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1
Show InChI InChI=1S/C18H23NO4/c1-12(7-13-3-5-17(23-2)6-4-13)19-11-18(22)14-8-15(20)10-16(21)9-14/h3-6,8-10,12,18-22H,7,11H2,1-2H3/t12-,18-/m0/s1
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n/an/an/an/a 2n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348429
PNG
(CHEMBL1800962 | US9492405, 41)
Show SMILES C[C@@H](Cc1ccc2ccccc2c1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C21H23NO3/c1-14(8-15-6-7-16-4-2-3-5-17(16)9-15)22-13-21(25)18-10-19(23)12-20(24)11-18/h2-7,9-12,14,21-25H,8,13H2,1H3/t14-,21-/m0/s1
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n/an/an/an/a 7.60n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50348430
PNG
(CHEMBL1800963 | US9492405, 44)
Show SMILES COc1ccc(C[C@@H](C)NC[C@H](O)c2cc(O)cc(O)c2)c2ccccc12 |r|
Show InChI InChI=1S/C22H25NO4/c1-14(23-13-21(26)16-10-17(24)12-18(25)11-16)9-15-7-8-22(27-2)20-6-4-3-5-19(15)20/h3-8,10-12,14,21,23-26H,9,13H2,1-2H3/t14-,21+/m1/s1
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n/an/an/an/a 3.90n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK 293 cells assessed as stimulation of cAMP accumulation by protein kinase binding...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Rattus norvegicus)
BDBM50213098
PNG
((R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, C...)
Show SMILES C[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17+/m1/s1
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n/an/an/an/a 73n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Rattus norvegicus)
BDBM50213106
PNG
((R,S)-(-)-fenoterol | CHEMBL229476 | US10617654, C...)
Show SMILES C[C@@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C17H21NO4/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13/h2-5,7-9,11,17-22H,6,10H2,1H3/t11-,17-/m0/s1
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n/an/an/an/a 575n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Rattus norvegicus)
BDBM50213099
PNG
((R,R)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Show SMILES COc1ccc(C[C@@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1
Show InChI InChI=1S/C18H23NO4/c1-12(7-13-3-5-17(23-2)6-4-13)19-11-18(22)14-8-15(20)10-16(21)9-14/h3-6,8-10,12,18-22H,7,11H2,1-2H3/t12-,18+/m1/s1
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n/an/an/an/a 186n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Rattus norvegicus)
BDBM50213120
PNG
((R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydrox...)
Show SMILES COc1ccc(C[C@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1
Show InChI InChI=1S/C18H23NO4/c1-12(7-13-3-5-17(23-2)6-4-13)19-11-18(22)14-8-15(20)10-16(21)9-14/h3-6,8-10,12,18-22H,7,11H2,1-2H3/t12-,18-/m0/s1
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n/an/an/an/a 506n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Rattus norvegicus)
BDBM50213115
PNG
((R,R)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21+/m1/s1
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n/an/an/an/a 59n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Rattus norvegicus)
BDBM50213110
PNG
((R,S)-(-)-5-{1-hydroxy-2-[1-methyl-2-(1-naphthyl)e...)
Show SMILES C[C@@H](Cc1cccc2ccccc12)NC[C@H](O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C21H23NO3/c1-14(9-16-7-4-6-15-5-2-3-8-20(15)16)22-13-21(25)17-10-18(23)12-19(24)11-17/h2-8,10-12,14,21-25H,9,13H2,1H3/t14-,21-/m0/s1
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n/an/an/an/a 103n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Rattus norvegicus)
BDBM50348426
PNG
(CHEMBL1800936 | US9492405, 48)
Show SMILES CC[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C18H23NO4/c1-2-14(7-12-3-5-15(20)6-4-12)19-11-18(23)13-8-16(21)10-17(22)9-13/h3-6,8-10,14,18-23H,2,7,11H2,1H3/t14-,18+/m1/s1
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n/an/an/an/a 8.55E+3n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Rattus norvegicus)
BDBM50348428
PNG
(CHEMBL1800961 | US9492405, 40)
Show SMILES C[C@H](Cc1ccc2ccccc2c1)NC[C@H](O)c1cc(O)cc(O)c1 |r|
Show InChI InChI=1S/C21H23NO3/c1-14(8-15-6-7-16-4-2-3-5-17(16)9-15)22-13-21(25)18-10-19(23)12-20(24)11-18/h2-7,9-12,14,21-25H,8,13H2,1H3/t14-,21+/m1/s1
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n/an/an/an/a 133n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Rattus norvegicus)
BDBM50348430
PNG
(CHEMBL1800963 | US9492405, 44)
Show SMILES COc1ccc(C[C@@H](C)NC[C@H](O)c2cc(O)cc(O)c2)c2ccccc12 |r|
Show InChI InChI=1S/C22H25NO4/c1-14(23-13-21(26)16-10-17(24)12-18(25)11-16)9-15-7-8-22(27-2)20-6-4-3-5-19(15)20/h3-8,10-12,14,21,23-26H,9,13H2,1-2H3/t14-,21+/m1/s1
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n/an/an/an/a 16n/an/an/an/a



Medical University of Lublin

Curated by ChEMBL


Assay Description
Agonist activity beta2-adrenergic receptor in rat ventricular myocytes assessed as cell contraction following electrical stimulation by optical edge ...


Bioorg Med Chem 18: 728-36 (2010)


Article DOI: 10.1016/j.bmc.2009.11.062
BindingDB Entry DOI: 10.7270/Q2R78FJF
More data for this
Ligand-Target Pair
Beta-3 adrenergic receptor


(Homo sapiens (Human))
BDBM50468332
PNG
(CHEMBL4294937)
Show SMILES OCC(NCCCc1ccccc1)c1ccc(O)c2[nH]c(=O)ccc12
Show InChI InChI=1S/C20H22N2O3/c23-13-17(21-12-4-7-14-5-2-1-3-6-14)15-8-10-18(24)20-16(15)9-11-19(25)22-20/h1-3,5-6,8-11,17,21,23-24H,4,7,12-13H2,(H,22,25)
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n/an/an/an/a<1.00E+4n/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human beta3 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay


Eur J Med Chem 152: 424-435 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.041
BindingDB Entry DOI: 10.7270/Q2GH9MNH
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50468333
PNG
(CHEMBL4279788)
Show SMILES OCC(NCCc1c[nH]c2ccccc12)c1ccc(O)c2[nH]c(=O)ccc12
Show InChI InChI=1S/C21H21N3O3/c25-12-18(15-5-7-19(26)21-16(15)6-8-20(27)24-21)22-10-9-13-11-23-17-4-2-1-3-14(13)17/h1-8,11,18,22-23,25-26H,9-10,12H2,(H,24,27)
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n/an/an/an/a 316n/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay


Eur J Med Chem 152: 424-435 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.041
BindingDB Entry DOI: 10.7270/Q2GH9MNH
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50468334
PNG
(CHEMBL4290441)
Show SMILES OCC(NCCCCOCCCCc1ccccc1)c1ccc(O)c2[nH]c(=O)ccc12
Show InChI InChI=1S/C25H32N2O4/c28-18-22(20-11-13-23(29)25-21(20)12-14-24(30)27-25)26-15-5-7-17-31-16-6-4-10-19-8-2-1-3-9-19/h1-3,8-9,11-14,22,26,28-29H,4-7,10,15-18H2,(H,27,30)
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n/an/an/an/a 251n/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay


Eur J Med Chem 152: 424-435 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.041
BindingDB Entry DOI: 10.7270/Q2GH9MNH
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50468335
PNG
(CHEMBL4280227)
Show SMILES OCC(NCCc1ccccc1O)c1ccc(O)c2[nH]c(=O)ccc12
Show InChI InChI=1S/C19H20N2O4/c22-11-15(20-10-9-12-3-1-2-4-16(12)23)13-5-7-17(24)19-14(13)6-8-18(25)21-19/h1-8,15,20,22-24H,9-11H2,(H,21,25)
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n/an/an/an/a 10n/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay


Eur J Med Chem 152: 424-435 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.041
BindingDB Entry DOI: 10.7270/Q2GH9MNH
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50468336
PNG
(CHEMBL4283676)
Show SMILES OCC(NCCc1ccc(O)cc1)c1ccc(O)c2[nH]c(=O)ccc12
Show InChI InChI=1S/C19H20N2O4/c22-11-16(20-10-9-12-1-3-13(23)4-2-12)14-5-7-17(24)19-15(14)6-8-18(25)21-19/h1-8,16,20,22-24H,9-11H2,(H,21,25)
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n/an/an/an/a 3.20n/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay


Eur J Med Chem 152: 424-435 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.041
BindingDB Entry DOI: 10.7270/Q2GH9MNH
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50468337
PNG
(CHEMBL4291941)
Show SMILES COc1cccc(CCNC(CO)c2ccc(O)c3[nH]c(=O)ccc23)c1
Show InChI InChI=1S/C20H22N2O4/c1-26-14-4-2-3-13(11-14)9-10-21-17(12-23)15-5-7-18(24)20-16(15)6-8-19(25)22-20/h2-8,11,17,21,23-24H,9-10,12H2,1H3,(H,22,25)
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n/an/an/an/a 2n/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay


Eur J Med Chem 152: 424-435 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.041
BindingDB Entry DOI: 10.7270/Q2GH9MNH
More data for this
Ligand-Target Pair
Beta-2 adrenergic receptor


(Homo sapiens (Human))
BDBM50468338
PNG
(CHEMBL4289233)
Show SMILES COc1ccc(CCNC(CO)c2ccc(O)c3[nH]c(=O)ccc23)cc1
Show InChI InChI=1S/C20H22N2O4/c1-26-14-4-2-13(3-5-14)10-11-21-17(12-23)15-6-8-18(24)20-16(15)7-9-19(25)22-20/h2-9,17,21,23-24H,10-12H2,1H3,(H,22,25)
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n/an/an/an/a 20n/an/an/an/a



Shenyang Pharmaceutical University

Curated by ChEMBL


Assay Description
Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay


Eur J Med Chem 152: 424-435 (2018)


Article DOI: 10.1016/j.ejmech.2018.04.041
BindingDB Entry DOI: 10.7270/Q2GH9MNH
More data for this
Ligand-Target Pair
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