| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-7 |
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| Ligand | BDBM74511 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_770045 (CHEMBL1832420) |
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| Ki | 15848.93±n/a nM |
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| Citation |  Akdemir, A; Rucktooa, P; Jongejan, A; Elk, R; Bertrand, S; Sixma, TK; Bertrand, D; Smit, AB; Leurs, R; de Graaf, C; de Esch, IJ Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors. Bioorg Med Chem19:6107-19 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuronal acetylcholine receptor subunit alpha-7 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-7 |
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| Synonyms: | ACHA7_HUMAN | CHRNA7 | Cholinergic, Nicotinic Alpha7 | NACHRA7 | Neuronal acetylcholine receptor protein alpha-7 subunit | Neuronal acetylcholine receptor subunit alpha-7 (nAChR-alpha 7) | Nicotinic acetylcholine receptor alpha-7 (alpha7 nAChR) |
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| Type: | n/a |
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| Mol. Mass.: | 56448.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | CHRNA7 (NACHRA7) |
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| Residue: | 502 |
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| Sequence: | MRCSPGGVWLALAASLLHVSLQGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLL
QIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADE
RFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL
QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIP
CVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFAST
MIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHK
QRRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHL
LHGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTI
ICTIGILMSAPNFVEAVSKDFA
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| BDBM74511 |
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| n/a |
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| Name | BDBM74511 |
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| Synonyms: | 1-(1-benzothien-3-ylmethyl)piperidine | 1-(1-benzothiophen-3-ylmethyl)piperidine;hydrochloride | 1-(benzothiophen-3-ylmethyl)piperidine;hydrochloride | CHEMBL1625371 | MLS000701611 | SMR000228504 | cid_15945777 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H17NS |
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| Mol. Mass. | 231.356 |
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| SMILES | C(N1CCCCC1)c1csc2ccccc12 |
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| Structure | 
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