Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Neuronal acetylcholine receptor subunit alpha-7 | ||
Ligand | BDBM50356470 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_775797 (CHEMBL1912300) | ||
Ki | 150±n/a nM | ||
Citation | Kombo, DC; Mazurov, A; Tallapragada, K; Hammond, PS; Chewning, J; Hauser, TA; Vasquez-Valdivieso, M; Yohannes, D; Talley, TT; Taylor, P; Caldwell, WS Docking studies of benzylidene anabaseine interactions witha7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of relateda7 selective ligands. Eur J Med Chem46:5625-35 (2011) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Neuronal acetylcholine receptor subunit alpha-7 | |||
Name: | Neuronal acetylcholine receptor subunit alpha-7 | ||
Synonyms: | ACHA7_RAT | Acra7 | Cholinergic, Nicotinic Alpha7 | Cholinergic, Nicotinic Alpha7/5-HT3 | Chrna7 | Neuronal acetylcholine receptor | Neuronal acetylcholine receptor (alpha7 nAChR) | Neuronal acetylcholine receptor subunit alpha 7 | Neuronal acetylcholine receptor subunit alpha-7 | Neuronal acetylcholine receptor subunit alpha-7 (nAChR alpha7) | Neuronal acetylcholine receptor subunit alpha-7 (nAChR) | ||
Type: | Enzyme | ||
Mol. Mass.: | 56502.44 | ||
Organism: | Rattus norvegicus (Rat) | ||
Description: | Q05941 | ||
Residue: | 502 | ||
Sequence: |
| ||
BDBM50356470 | |||
n/a | |||
Name | BDBM50356470 | ||
Synonyms: | CHEMBL1911858 | ||
Type | Small organic molecule | ||
Emp. Form. | C15H19N3O2 | ||
Mol. Mass. | 273.3303 | ||
SMILES | O=C1CC(=NCC2(CN3CCC2CC3)N1)c1ccco1 |c:3,(-1.44,-20.48,;-1.12,-21.98,;.38,-22.34,;1.02,-23.74,;.34,-25.13,;-1.18,-25.45,;-2.37,-24.47,;-2.37,-26.01,;-3.7,-26.77,;-5.03,-26.01,;-5.03,-24.47,;-3.7,-23.69,;-2.95,-25.02,;-4.29,-25.78,;-2.35,-22.93,;2.57,-23.76,;3.49,-22.53,;4.95,-23.02,;4.92,-24.56,;3.45,-25.02,)| | ||
Structure |