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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Ligand | BDBM50356473 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_775797 (CHEMBL1912300) | ||
| Ki | 290±n/a nM | ||
| Citation |  Kombo, DC; Mazurov, A; Tallapragada, K; Hammond, PS; Chewning, J; Hauser, TA; Vasquez-Valdivieso, M; Yohannes, D; Talley, TT; Taylor, P; Caldwell, WS Docking studies of benzylidene anabaseine interactions witha7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of relateda7 selective ligands. Eur J Med Chem46:5625-35 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuronal acetylcholine receptor subunit alpha-7 | |||
| Name: | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Synonyms: | ACHA7_RAT | Acra7 | Cholinergic, Nicotinic Alpha7 | Cholinergic, Nicotinic Alpha7/5-HT3 | Chrna7 | Neuronal acetylcholine receptor | Neuronal acetylcholine receptor (alpha7 nAChR) | Neuronal acetylcholine receptor subunit alpha 7 | Neuronal acetylcholine receptor subunit alpha-7 | Neuronal acetylcholine receptor subunit alpha-7 (nAChR alpha7) | Neuronal acetylcholine receptor subunit alpha-7 (nAChR) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 56502.44 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | Q05941 | ||
| Residue: | 502 | ||
| Sequence: |
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| BDBM50356473 | |||
| n/a | |||
| Name | BDBM50356473 | ||
| Synonyms: | CHEMBL1911864 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H19N3O | ||
| Mol. Mass. | 257.3309 | ||
| SMILES | Oc1ccccc1C1=NCC2(CN3CCC2CC3)N1 |t:8,(7.52,-.14,;6.43,.95,;6.82,2.44,;5.73,3.53,;4.24,3.12,;3.85,1.63,;4.94,.55,;4.54,-.93,;5.51,-2.13,;4.67,-3.42,;3.18,-3.03,;3.18,-4.57,;1.86,-5.34,;.52,-4.57,;.52,-3.03,;1.86,-2.25,;2.61,-3.58,;1.27,-4.35,;3.1,-1.49,)| | ||
| Structure | 
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