| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
|---|
| Ligand | BDBM50357630 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_788408 (CHEMBL1918136) |
|---|
| IC50 | 14±n/a nM |
|---|
| Citation |  Iwahashi, M; Naganawa, A; Kinoshita, A; Shimabukuro, A; Nishiyama, T; Ogawa, S; Matsunaga, Y; Tsukamoto, K; Okada, Y; Matsumoto, R; Nambu, F; Oumi, R; Odagaki, Y; Katagi, J; Yano, K; Tani, K; Nakai, H; Toda, M Discovery of new orally active prostaglandin D2 receptor antagonists. Bioorg Med Chem19:6935-48 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin D2 receptor |
|---|
| Name: | Prostaglandin D2 receptor |
|---|
| Synonyms: | PD2R_MOUSE | Prostanoid DP receptor | Ptgdr |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40018.63 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_788408 |
|---|
| Residue: | 357 |
|---|
| Sequence: | MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVF
YVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTL
QLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGT
WCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSR
DRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSE
DLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
|
|
|
|---|
| BDBM50357630 |
|---|
| n/a |
|---|
| Name | BDBM50357630 |
|---|
| Synonyms: | CHEMBL1915859 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H24ClNO5 |
|---|
| Mol. Mass. | 465.925 |
|---|
| SMILES | Cc1cc(OC[C@@H]2Cc3ccccc3O2)cc(C)c1C(=O)Nc1cc(CC(O)=O)ccc1Cl |r| |
|---|
| Structure | 
|
|---|
Search and Browse
