| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
|---|
| Ligand | BDBM50365416 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_807246 (CHEMBL1960176) |
|---|
| IC50 | 20±n/a nM |
|---|
| Citation |  Omori, N; Kouyama, N; Yukimasa, A; Watanabe, K; Yokota, Y; Tanioka, H; Nambu, H; Yukioka, H; Sato, N; Tanaka, Y; Sekiguchi, K; Okuno, T Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist. Bioorg Med Chem Lett22:2020-3 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuropeptide Y receptor type 5 |
|---|
| Name: | Neuropeptide Y receptor type 5 |
|---|
| Synonyms: | NPY-Y5 | NPY5R_MOUSE | Neuropeptide Y receptor Y5 | Neuropeptide Y receptor type 5 (NPY Y5) | Npy5 | Npy5r |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52807.91 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | O70342 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MEVKLEEHFNKTFVTENNTAASQNTASPAWEDYRGTENNTSAARNTAFPVWEDYRGSVDD
LQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTL
TSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFL
IATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQ
YILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLHPSKKSRDQAKPPSTQKWSY
SFIRKHRRRYSKKTACVLPAPAGPSQEKHLTVPENPGSVRSQLSPSSKVIPGVPICFEVK
PEESSDAQEMRVKRSLTRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISN
RHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
|
|
|
|---|
| BDBM50365416 |
|---|
| n/a |
|---|
| Name | BDBM50365416 |
|---|
| Synonyms: | CHEMBL1585484 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18ClN3O3S2 |
|---|
| Mol. Mass. | 423.937 |
|---|
| SMILES | Clc1cccc(CSc2nc3ccc(cc3[nH]2)S(=O)(=O)N2CCOCC2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
