| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50366261 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201273 (CHEMBL804962) |
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| Ki | 31±n/a nM |
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| Citation |  Prucher, H; Gottschlich, R; Haase, A; Stohrer, M; Seyfried, C (5S)-3-aryl-5-(1-piperidinylmethyl)-2-oxazolidinones, a new class of potential neuroleptics with a high affinity for sigma receptors Bioorg Med Chem Lett2:165-170 (1992) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50366261 |
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| n/a |
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| Name | BDBM50366261 |
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| Synonyms: | CHEMBL47678 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28N2O6 |
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| Mol. Mass. | 440.4889 |
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| SMILES | COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccc3OCCOc3c2)OC1=O |
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| Structure | 
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