Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50366273 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_201274 (CHEMBL804963) |
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Ki | 7±n/a nM |
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Citation | Prucher, H; Gottschlich, R; Haase, A; Stohrer, M; Seyfried, C (5S)-3-aryl-5-(1-piperidinylmethyl)-2-oxazolidinones, a new class of potential neuroleptics with a high affinity for sigma receptors Bioorg Med Chem Lett2:165-170 (1992) Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25124.85 |
Organism: | Homo sapiens (Human) |
Description: | Q99720 |
Residue: | 223 |
Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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BDBM50366273 |
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n/a |
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Name | BDBM50366273 |
Synonyms: | CHEMBL417357 |
Type | Small organic molecule |
Emp. Form. | C22H26N2O4 |
Mol. Mass. | 382.4528 |
SMILES | COc1ccc(cc1)N1C[C@H](CN2CCC(O)(CC2)c2ccccc2)OC1=O |
Structure |
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