| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Aminopeptidase N |
|---|
| Ligand | BDBM50075326 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_35494 |
|---|
| IC50 | 108000±n/a nM |
|---|
| Citation |  Shimazawa, R; Takayama, H; Kato, F; Kato, M; Hashimoto, Y Nonpeptide small-molecular inhibitors of dipeptidyl peptidase IV: N-phenylphthalimide analogs. Bioorg Med Chem Lett9:559-62 (1999) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Aminopeptidase N |
|---|
| Name: | Aminopeptidase N |
|---|
| Synonyms: | AMPN_HUMAN | ANPEP | APN | Alanyl aminopeptidase | Aminopeptidase | CD13 | CD_antigen=CD13 | Microsomal aminopeptidase | Myeloid plasma membrane glycoprotein CD13 | PEPN | gp150 | hAPN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 109522.63 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1507526 |
|---|
| Residue: | 967 |
|---|
| Sequence: | MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSPVASTTPSASATTNPA
SATTLDQSKAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVI
IIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDS
EFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHP
KDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLI
RIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLV
TYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYL
GADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKG
ASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIM
NRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDY
WLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQ
IINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKN
YLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWM
ENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWI
LNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSN
LIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQ
WFTENSK
|
|
|
|---|
| BDBM50075326 |
|---|
| n/a |
|---|
| Name | BDBM50075326 |
|---|
| Synonyms: | 4-Amino-2-(2,6-dimethyl-phenyl)-isoindole-1,3-dione | CHEMBL315471 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14N2O2 |
|---|
| Mol. Mass. | 266.2946 |
|---|
| SMILES | Cc1cccc(C)c1N1C(=O)c2cccc(N)c2C1=O |
|---|
| Structure | 
|
|---|
Search and Browse
