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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50085377 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_144000 | ||
| IC50 | 54±n/a nM | ||
| Citation |  McNally, JJ; Youngman, MA; Lovenberg, TW; Nepomuceno, DH; Wilson, SJ; Dax, SL N-(sulfonamido)alkyl[tetrahydro-1H-benzo[e]indol-2-yl]amines: potent antagonists of human neuropeptide Y Y5 receptor. Bioorg Med Chem Lett10:213-6 (2000) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50085377 | |||
| n/a | |||
| Name | BDBM50085377 | ||
| Synonyms: | CHEMBL302584 | N-{4-[(7-Chloro-3a,4,5,9b-tetrahydro-1H-benzo[e]indol-2-ylamino)-methyl]-cyclohexylmethyl}-benzenesulfonamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H32ClN3O2S | ||
| Mol. Mass. | 486.069 | ||
| SMILES | Clc1ccc2C3CC(NC[C@H]4CC[C@H](CNS(=O)(=O)c5ccccc5)CC4)=NC3CCc2c1 |wU:10.9,wD:13.13,c:28,(-3.57,-2.98,;-2.22,-2.21,;-2.22,-.65,;-.89,.12,;.45,-.65,;1.78,.13,;2.1,1.64,;3.65,1.8,;4.42,3.13,;5.95,3.13,;6.73,1.8,;8.26,1.8,;9.03,.46,;8.26,-.87,;9.03,-2.21,;10.58,-2.22,;11.35,-3.55,;10.02,-4.33,;12.68,-2.78,;12.11,-4.89,;11.32,-6.2,;12.09,-7.54,;13.62,-7.54,;14.39,-6.2,;13.63,-4.89,;6.72,-.87,;5.95,.46,;4.26,.39,;3.12,-.64,;3.12,-2.21,;1.78,-2.98,;.44,-2.2,;-.89,-2.98,)| | ||
| Structure | 
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