| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50367602 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_62404 |
|---|
| Ki | 3750±n/a nM |
|---|
| Citation |  Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB Synthesis and pharmacological characterization of 1-phenyl-, 4-phenyl-, and 1-benzyl-1,2,3,4-tetrahydroisoquinolines as dopamine receptor ligands. J Med Chem31:1941-6 (1988) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50367602 |
|---|
| n/a |
|---|
| Name | BDBM50367602 |
|---|
| Synonyms: | CHEMBL65397 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H14ClNO |
|---|
| Mol. Mass. | 259.731 |
|---|
| SMILES | Oc1cc2[C@@H](NCCc2cc1Cl)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
