| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine deaminase |
|---|
| Ligand | BDBM50034908 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_30803 |
|---|
| Ki | 7±n/a nM |
|---|
| Citation |  Cristalli, G; Franchetti, P; Grifantini, M; Vittori, S; Lupidi, G; Riva, F; Bordoni, T; Geroni, C; Verini, MA Adenosine deaminase inhibitors. Synthesis and biological activity of deaza analogues of erythro-9-(2-hydroxy-3-nonyl)adenine. J Med Chem31:390-3 (1988) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine deaminase |
|---|
| Name: | Adenosine deaminase |
|---|
| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40910.44 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | n/a |
|---|
| Residue: | 363 |
|---|
| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
|
|
|
|---|
| BDBM50034908 |
|---|
| n/a |
|---|
| Name | BDBM50034908 |
|---|
| Synonyms: | (2R,3S)-3-((R)-6-Amino-purin-9-yl)-nonan-2-ol | (2R,3S)-3-(6-Amino-purin-9-yl)-nonan-2-ol | (2R,3S)-3-(6-amino-9H-purin-9-yl)nonan-2-ol | (EHNA)3-(6-Amino-purin-9-yl)-nonan-2-ol | 3-(6-Amino-purin-9-yl)-nonan-2-ol | 3-(6-Amino-purin-9-yl)-nonan-2-ol(EHNA) | CHEMBL50378 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H23N5O |
|---|
| Mol. Mass. | 277.3653 |
|---|
| SMILES | CCCCCC[C@@H]([C@@H](C)O)n1cnc2c(N)ncnc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
