Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50453048 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_148696 (CHEMBL751069) |
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IC50 | 73000±n/a nM |
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Citation | Hruby, VJ; Toth, G; Gehrig, CA; Kao, LF; Knapp, R; Lui, GK; Yamamura, HI; Kramer, TH; Davis, P; Burks, TF Topographically designed analogues of [D-Pen,D-Pen5]enkephalin. J Med Chem34:1823-30 (1991) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 44503.11 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor. |
Residue: | 398 |
Sequence: | MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50453048 |
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n/a |
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Name | BDBM50453048 |
Synonyms: | CHEMBL2115042 |
Type | Small organic molecule |
Emp. Form. | C31H41N5O7S2 |
Mol. Mass. | 659.817 |
SMILES | [H][C@@]1(NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC(C)(C)[C@H](NC1=O)C(O)=O)[C@H](C)c1ccccc1 |
Structure |
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