Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50004107 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_226544 (CHEMBL846484) |
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IC50 | 2060±n/a nM |
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Citation | Kimes, AS; Wilson, AA; Scheffel, U; Campbell, BG; London, ED Radiosynthesis, cerebral distribution, and binding of [125I]-1-(p-iodophenyl)-3-(1-adamantyl)guanidine, a ligand for sigma binding sites. J Med Chem35:4683-9 (1993) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25124.85 |
Organism: | Homo sapiens (Human) |
Description: | Q99720 |
Residue: | 223 |
Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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BDBM50004107 |
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n/a |
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Name | BDBM50004107 |
Synonyms: | 1-(1-Thiophen-2-yl-cyclohexyl)-piperidine | CHEMBL279676 | Tenocyclidine |
Type | Small organic molecule |
Emp. Form. | C15H23NS |
Mol. Mass. | 249.415 |
SMILES | C1CCN(CC1)C1(CCCCC1)c1cccs1 |
Structure |
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