Reaction Details | |||
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Target | Gastrin/cholecystokinin type B receptor | ||
Ligand | BDBM50005816 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_48256 | ||
IC50 | 351±n/a nM | ||
Citation | Fincham, CI; Higginbottom, M; Hill, DR; Horwell, DC; O'Toole, JC; Ratcliffe, GS; Rees, DC; Roberts, E Amide bond replacements incorporated into CCK-B selective"dipeptoids". J Med Chem35:1472-84 (1992) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Gastrin/cholecystokinin type B receptor | |||
Name: | Gastrin/cholecystokinin type B receptor | ||
Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 49196.59 | ||
Organism: | MOUSE | ||
Description: | Cholecystokinin A CCKBR MOUSE::P56481 | ||
Residue: | 453 | ||
Sequence: |
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BDBM50005816 | |||
n/a | |||
Name | BDBM50005816 | ||
Synonyms: | CHEMBL284361 | N-{2-[2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionyloxy]-1-phenyl-ethyl}-succinamic acid methyl ester;0.5H2O | ||
Type | Small organic molecule | ||
Emp. Form. | C36H43N3O7 | ||
Mol. Mass. | 629.7425 | ||
SMILES | COC(=O)CCC(=O)N[C@H](COC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)c1ccccc1 |wU:33.34,37.38,wD:9.8,35.42,31.33,TLB:29:30:36:33.38.34,THB:32:31:36:33.38.34,32:33:36:30.31.39,(24.56,-12.48,;23.08,-12.88,;21.98,-11.81,;22.34,-10.31,;20.48,-12.24,;19.39,-11.15,;17.92,-11.56,;17.53,-13.07,;16.79,-10.5,;17.18,-9.02,;16.31,-7.74,;14.77,-7.84,;13.9,-6.58,;14.58,-5.2,;12.4,-6.69,;13.16,-8.02,;11.15,-5.79,;11.31,-4.25,;10.15,-3.24,;10.76,-1.83,;12.3,-1.97,;13.42,-.94,;14.9,-1.39,;15.22,-2.92,;14.09,-3.96,;12.62,-3.48,;11.62,-8.02,;10.08,-8,;9.32,-6.65,;9.28,-9.32,;7.74,-9.28,;6.36,-8.71,;5.02,-9.19,;5.02,-10.66,;3.83,-11.94,;5.31,-11.52,;6.72,-12.08,;7.74,-10.81,;6.33,-11.15,;5.31,-9.93,;18.55,-8.29,;19.84,-9.12,;21.21,-8.42,;21.27,-6.88,;19.96,-6.04,;18.59,-6.77,)| | ||
Structure |