Reaction Details | |||
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Target | Cholecystokinin receptor type A | ||
Ligand | BDBM50005817 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_50060 | ||
IC50 | 808±n/a nM | ||
Citation | Fincham, CI; Higginbottom, M; Hill, DR; Horwell, DC; O'Toole, JC; Ratcliffe, GS; Rees, DC; Roberts, E Amide bond replacements incorporated into CCK-B selective"dipeptoids". J Med Chem35:1472-84 (1992) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Cholecystokinin receptor type A | |||
Name: | Cholecystokinin receptor type A | ||
Synonyms: | CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 49676.37 | ||
Organism: | RAT | ||
Description: | Cholecystokinin central 0 RAT::P30551 | ||
Residue: | 444 | ||
Sequence: |
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BDBM50005817 | |||
n/a | |||
Name | BDBM50005817 | ||
Synonyms: | CHEMBL287682 | [2-(1H-Indol-3-yl)-1-methyl-1-phenethylthiocarbamoyl-ethyl]-carbamic acid adamantan-2-yl ester | ||
Type | Small organic molecule | ||
Emp. Form. | C31H37N3O2S | ||
Mol. Mass. | 515.709 | ||
SMILES | CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=S)NCCc1ccccc1 |wU:19.20,17.29,wD:21.28,23.26,TLB:15:16:22:19.24.20,THB:18:17:22:19.24.20,18:19:16.17.25:22,(13.87,-8.61,;13.1,-7.28,;11.85,-6.38,;12.01,-4.84,;10.85,-3.83,;11.49,-2.42,;13,-2.57,;14.15,-1.52,;15.6,-1.99,;15.95,-3.51,;14.8,-4.53,;13.35,-4.07,;12.33,-8.6,;10.79,-8.58,;10.04,-7.23,;10.01,-9.89,;8.47,-9.86,;7.07,-9.28,;5.72,-9.76,;5.74,-11.24,;4.53,-12.52,;6.04,-12.11,;7.44,-12.67,;8.47,-11.4,;7.06,-11.74,;6.03,-10.52,;14.63,-7.17,;15.3,-5.79,;15.5,-8.44,;17.01,-8.32,;17.88,-9.6,;19.26,-8.89,;19.31,-7.36,;20.67,-6.64,;21.99,-7.45,;21.92,-8.99,;20.54,-9.72,)| | ||
Structure |