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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cholecystokinin receptor type A | ||
| Ligand | BDBM50005814 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_50060 | ||
| IC50 | 1460±n/a nM | ||
| Citation |  Fincham, CI; Higginbottom, M; Hill, DR; Horwell, DC; O'Toole, JC; Ratcliffe, GS; Rees, DC; Roberts, E Amide bond replacements incorporated into CCK-B selective"dipeptoids". J Med Chem35:1472-84 (1992) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cholecystokinin receptor type A | |||
| Name: | Cholecystokinin receptor type A | ||
| Synonyms: | CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 49676.37 | ||
| Organism: | RAT | ||
| Description: | Cholecystokinin central 0 RAT::P30551 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM50005814 | |||
| n/a | |||
| Name | BDBM50005814 | ||
| Synonyms: | CHEMBL422941 | [1-[(1-Hydroxymethyl-2-phenyl-ethyl)-methyl-carbamoyl]-2-(1H-indol-3-yl)-ethyl]-carbamic acid adamantan-2-yl ester;0.85chloroform | ||
| Type | Small organic molecule | ||
| Emp. Form. | C32H39N3O4 | ||
| Mol. Mass. | 529.6698 | ||
| SMILES | CN(C(CO)Cc1ccccc1)C(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 |wU:32.34,36.38,wD:34.42,30.33,TLB:28:29:35:32.37.33,THB:31:30:35:32.37.33,31:32:35:29.30.38,(14.54,-9.86,;15.22,-8.47,;16.76,-8.35,;17.43,-6.97,;18.97,-6.87,;17.62,-9.64,;19.16,-9.51,;20.02,-10.79,;21.54,-10.68,;22.21,-9.28,;21.35,-8.02,;19.81,-8.13,;14.35,-7.2,;15.02,-5.82,;12.84,-7.31,;11.59,-6.42,;11.75,-4.88,;10.6,-3.86,;11.21,-2.45,;12.75,-2.6,;13.87,-1.55,;15.35,-2.02,;15.67,-3.54,;14.53,-4.57,;13.07,-4.11,;12.06,-8.63,;10.52,-8.61,;9.76,-7.26,;9.73,-9.92,;8.19,-9.89,;6.81,-9.31,;5.46,-9.8,;5.46,-11.27,;4.28,-12.55,;5.77,-12.14,;7.16,-12.7,;8.19,-11.43,;6.78,-11.77,;5.75,-10.55,)| | ||
| Structure | 
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