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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Gastrin/cholecystokinin type B receptor | ||
| Ligand | BDBM50005828 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_48256 | ||
| IC50 | 1190±n/a nM | ||
| Citation |  Fincham, CI; Higginbottom, M; Hill, DR; Horwell, DC; O'Toole, JC; Ratcliffe, GS; Rees, DC; Roberts, E Amide bond replacements incorporated into CCK-B selective"dipeptoids". J Med Chem35:1472-84 (1992) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Gastrin/cholecystokinin type B receptor | |||
| Name: | Gastrin/cholecystokinin type B receptor | ||
| Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin receptor | GASR_MOUSE | Gastrin/cholecystokinin type B receptor | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 49196.59 | ||
| Organism: | MOUSE | ||
| Description: | Cholecystokinin A CCKBR MOUSE::P56481 | ||
| Residue: | 453 | ||
| Sequence: |
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| BDBM50005828 | |||
| n/a | |||
| Name | BDBM50005828 | ||
| Synonyms: | 2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-thiopropionic acid S-phenethyl ester | CHEMBL288038 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H36N2O3S | ||
| Mol. Mass. | 516.694 | ||
| SMILES | CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)SCCc1ccccc1 |wU:19.20,17.29,wD:21.28,23.26,TLB:15:16:22:19.24.20,THB:18:17:22:19.24.20,18:19:16.17.25:22,(13.87,-8.6,;13.1,-7.26,;11.85,-6.36,;12.01,-4.82,;10.85,-3.82,;11.48,-2.41,;13,-2.54,;14.15,-1.52,;15.6,-1.97,;15.94,-3.5,;14.8,-4.53,;13.34,-4.05,;12.33,-8.6,;10.79,-8.58,;10.04,-7.23,;10.01,-9.89,;8.47,-9.86,;7.07,-9.28,;5.72,-9.76,;5.74,-11.24,;4.53,-12.51,;6.04,-12.09,;7.44,-12.65,;8.47,-11.39,;7.06,-11.72,;6.03,-10.5,;14.63,-7.15,;15.3,-5.77,;15.49,-8.41,;17.01,-8.32,;17.88,-9.59,;19.26,-8.86,;19.31,-7.35,;20.67,-6.62,;21.98,-7.45,;21.92,-8.99,;20.54,-9.7,)| | ||
| Structure | 
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