| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50039189 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201099 (CHEMBL807414) |
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| Ki | 22±n/a nM |
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| Citation |  Calderon, SN; Izenwasser, S; Heller, B; Gutkind, JS; Mattson, MV; Su, TP; Newman, AH Novel 1-phenylcycloalkanecarboxylic acid derivatives are potent and selective sigma 1 ligands. J Med Chem37:2285-91 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25266.54 |
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| Organism: | RAT |
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| Description: | Q9R0C9 |
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| Residue: | 223 |
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| Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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| BDBM50039189 |
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| n/a |
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| Name | BDBM50039189 |
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| Synonyms: | 1-(3,4-Dichloro-phenyl)-cyclohexanecarboxylic acid 2-diethylamino-ethoxymethyl ester | CHEMBL75217 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H29Cl2NO3 |
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| Mol. Mass. | 402.355 |
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| SMILES | CCN(CC)CCOCOC(=O)C1(CCCCC1)c1ccc(Cl)c(Cl)c1 |
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| Structure | 
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