Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50039198 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_201099 (CHEMBL807414) |
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Ki | 32±n/a nM |
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Citation | Calderon, SN; Izenwasser, S; Heller, B; Gutkind, JS; Mattson, MV; Su, TP; Newman, AH Novel 1-phenylcycloalkanecarboxylic acid derivatives are potent and selective sigma 1 ligands. J Med Chem37:2285-91 (1994) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25266.54 |
Organism: | RAT |
Description: | Q9R0C9 |
Residue: | 223 |
Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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BDBM50039198 |
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n/a |
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Name | BDBM50039198 |
Synonyms: | 1-(3,4-Dichloro-phenyl)-cyclohexanecarboxylic acid (2-morpholin-4-yl-ethoxymethyl)-amide | CHEMBL307668 |
Type | Small organic molecule |
Emp. Form. | C20H28Cl2N2O3 |
Mol. Mass. | 415.354 |
SMILES | Clc1ccc(cc1Cl)C1(CCCCC1)C(=O)NCOCCN1CCOCC1 |
Structure |
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