| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H1 receptor |
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| Ligand | BDBM50056946 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_84717 (CHEMBL695165) |
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| Ki | 42±n/a nM |
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| Citation |  el Ahmad, Y; Laurent, E; Maillet, P; Talab, A; Teste, JF; Dokhan, R; Tran, G; Ollivier, R New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands. J Med Chem40:952-60 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H1 receptor |
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| Name: | Histamine H1 receptor |
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| Synonyms: | HISTAMINE H1 | HRH1_RAT | Hrh1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 55716.35 |
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| Organism: | RAT |
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| Description: | HISTAMINE H1 HRH1 RAT::P31390 |
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| Residue: | 486 |
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| Sequence: | MSFANTSSTFEDKMCEGNRTAMASPQLLPLVVVLSSISLVTVGLNLLVLYAVHSERKLHT
VGNLYIVSLSVADLIVGAVVMPMNILYLIMTKWSLGRPLCLFWLSMDYVASTASIFSVFI
LCIDRYRSVQQPLRYLRYRTKTRASATILGAWFFSFLWVIPILGWHHFMPPAPELREDKC
ETDFYNVTWFKIMTAIINFYLPTLLMLWFYVKIYKAVRRHCQHRQLTNGSLPSFSELKLR
SDDTKEGAKKPGRESPWGVLKRPSRDPSVGLDQKSTSEDPKMTSPTVFSQEGERETRPCF
RLDIMQKQSVAEGDVRGSKANDQALSQPKMDEQSLNTCRRISETSEDQTLVDQQSFSRTT
DSDTSIEPGPGRVKSRSGSNSGLDYIKITWKRLRSHSRQYVSGLHLNRERKAAKQLGFIM
AAFILCWIPYFIFFMVIAFCKSCCSEPMHMFTIWLGYINSTLNPLIYPLCNENFKKTFKK
ILHIRS
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| BDBM50056946 |
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| n/a |
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| Name | BDBM50056946 |
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| Synonyms: | 1-(4-Fluoro-phenyl)-4-[4-(1,2,3,4-tetrahydro-naphthalen-1-yl)-piperazin-1-yl]-butan-1-one | CHEMBL366388 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H29FN2O |
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| Mol. Mass. | 380.4983 |
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| SMILES | Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C1CCCc2ccccc12 |
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| Structure | 
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