| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50001859 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_58985 (CHEMBL668650) |
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| Ki | >1000±n/a nM |
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| Citation |  el Ahmad, Y; Laurent, E; Maillet, P; Talab, A; Teste, JF; Dokhan, R; Tran, G; Ollivier, R New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands. J Med Chem40:952-60 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | D(1A) dopamine receptor | DOPAMINE D1 | DRD1_MOUSE | Dopamine D1 receptor | Dopamine receptor | Drd1 | Drd1a | Gpcr15 |
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| Type: | Enzyme |
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| Mol. Mass.: | 49613.93 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | Q61616 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDETGLPVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
AEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTTGNGNPVECSQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVMFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKREEAGGIPKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50001859 |
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| n/a |
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| Name | BDBM50001859 |
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| Synonyms: | (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione | 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride) | 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone) | 8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione | BUSPAR | BUSPIRONE | CHEMBL49 | US10562853, Compound Buspirone |
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| Type | Small organic molecule |
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| Emp. Form. | C21H31N5O2 |
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| Mol. Mass. | 385.5031 |
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| SMILES | O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 |
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| Structure | 
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