| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50064556 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_62547 (CHEMBL674060) |
|---|
| Ki | 1.1±n/a nM |
|---|
| Citation |  Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL Orally active benzamide antipsychotic agents with affinity for dopamine D2, serotonin 5-HT1A, and adrenergic alpha1 receptors. J Med Chem41:1997-2009 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50064556 |
|---|
| n/a |
|---|
| Name | BDBM50064556 |
|---|
| Synonyms: | 1-(2-Isopropoxy-phenyl)-4-[3-(piperidine-1-sulfonyl)-benzyl]-piperazine | CHEMBL301465 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H35N3O3S |
|---|
| Mol. Mass. | 457.629 |
|---|
| SMILES | CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)S(=O)(=O)N2CCCCC2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
