Ki Summary

Reaction Details

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Target

Glucagon receptor

Ligand

BDBM50098571

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_70921 (CHEMBL683739)

IC50

1.5±n/a nM

Citation

Trivedi, D; Lin, Y; Ahn, JM; Siegel, M; Mollova, NN; Schram, KH; Hruby, VJ Design and synthesis of conformationally constrained glucagon analogues. J Med Chem43:1714-22 (2000) [PubMed]

More Info.:

Get all data from this article, Assay Method

Glucagon receptor

Name:

Glucagon receptor

Synonyms:

GL-R | GLR_RAT | Gcgr

Type:

PROTEIN

Mol. Mass.:

55053.40

Organism:

Rattus norvegicus

Description:

ChEMBL_1450588

Residue:

485

Sequence:

MLLTQLHCPYLLLLLVVLSCLPKAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCN
RTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQSWRDAS
QCQMDDDEIEVQKGVAKMYSSYQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGN
LFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAVAGCRVATVIMQYGIIANY
CWLLVEGVYLYSLLSITTFSEKSFFSLYLCIGWGSPLLFVIPWVVVKCLFENVQCWTSND
NMGFWWILRIPVLLAILINFFIFVRIIHLLVAKLRAHQMHYADYKFRLARSTLTLIPLLG
VHEVVFAFVTDEHAQGTLRSTKLFFDLFFSSFQGLLVAVLYCFLNKEVQAELLRRWRRWQ
EGKALQEERMASSHGSHMAPAGTCHGDPCEKLQLMSAGSSSGTGCEPSAKTSLASSLPRL
ADSPT

BDBM50098571

n/a

Name

BDBM50098571

Synonyms:

CHEMBL266481 | GLUCAGON | His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Leu-Met-Asn-Thr (Glucagon) | His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr | His-Ser-Gln-GlyThr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-asn-Thr | HisSerGluPheTyrPheTyrLysSerTyrAspArgTyrLeuAspSerLysLysAlaGluGluLeuTrpGluValPheAsp

Type

Small organic molecule

Emp. Form.

C153H225N43O49S

Mol. Mass.

3482.747

SMILES

n/a

Structure