| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50106318 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_138939 (CHEMBL745919) |
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| Ki | 56±n/a nM |
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| Citation |  Zhang, Y; Joseph, DB; Bowen, WD; Flippen-Anderson, JL; Dersch, CM; Rothman, RB; Jacobson, AE; Rice, KC Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues. J Med Chem44:3937-45 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50106318 |
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| n/a |
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| Name | BDBM50106318 |
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| Synonyms: | 3-(2-Benzhydryloxy-ethyl)-8-methyl-8-aza-bicyclo[3.2.1]octane | CHEMBL341301 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H29NO |
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| Mol. Mass. | 335.4825 |
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| SMILES | CN1C2CCC1CC(CCOC(c1ccccc1)c1ccccc1)C2 |THB:8:7:1:3.4| |
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| Structure | 
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