| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50097451 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30023 (CHEMBL641314) |
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| Ki | 570±n/a nM |
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| Citation |  van Muijlwijk-Koezen, JE; Timmerman, H; Vollinga, RC; Frijtag von Drabbe Künzel, J; de Groote, M; Visser, S; IJzerman, AP Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists. J Med Chem44:749-62 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 45015.65 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat A2A receptors expressed in CHO cells. |
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| Residue: | 410 |
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| Sequence: | MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
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| BDBM50097451 |
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| n/a |
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| Name | BDBM50097451 |
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| Synonyms: | 4-Hydroxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide(LUF5437) | CHEMBL164745 | LUF-5437 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11N3O2S |
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| Mol. Mass. | 297.332 |
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| SMILES | Oc1ccc(cc1)C(=O)Nc1nc(ns1)-c1ccccc1 |
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| Structure | 
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