| Reaction Details |
|---|
 | Report a problem with these data |
| Target | MO15-related protein kinase Pfmrk |
|---|
| Ligand | BDBM50131991 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_52679 (CHEMBL666134) |
|---|
| IC50 | 150000±n/a nM |
|---|
| Citation |  Woodard, CL; Li, Z; Kathcart, AK; Terrell, J; Gerena, L; Lopez-Sanchez, M; Kyle, DE; Bhattacharjee, AK; Nichols, DA; Ellis, W; Prigge, ST; Geyer, JA; Waters, NC Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases. J Med Chem46:3877-82 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| MO15-related protein kinase Pfmrk |
|---|
| Name: | MO15-related protein kinase Pfmrk |
|---|
| Synonyms: | Protein kinase Pfmrk |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 37992.30 |
|---|
| Organism: | Plasmodium falciparum |
|---|
| Description: | ChEMBL_640752 |
|---|
| Residue: | 324 |
|---|
| Sequence: | MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLL
REIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQI
LNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLN
LTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFL
LGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAED
AMKHRYFFNDPLPCDISQLPFNDL
|
|
|
|---|
| BDBM50131991 |
|---|
| n/a |
|---|
| Name | BDBM50131991 |
|---|
| Synonyms: | 3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-one | CHEMBL126602 | cid_682361 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H11NO2 |
|---|
| Mol. Mass. | 249.264 |
|---|
| SMILES | O=C(\C=C1\C(=O)Nc2ccccc12)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
