| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50142981 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157865 (CHEMBL764753) |
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| Ki | 295±n/a nM |
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| Citation |  Reid, RC; Pattenden, LK; Tyndall, JD; Martin, JL; Walsh, T; Fairlie, DP Countering cooperative effects in protease inhibitors using constrained beta-strand-mimicking templates in focused combinatorial libraries. J Med Chem47:1641-51 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50142981 |
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| n/a |
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| Name | BDBM50142981 |
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| Synonyms: | CHEMBL46967 | Quinoline-8-sulfonic acid [(S)-2-(R)-hydroxy-2-((S)-10-isopropyl-8,11-dioxo-2-oxa-9,12-diaza-bicyclo[13.2.2]nonadeca-1(18),15(19),16-trien-13-yl)-ethyl]-(3-methyl-butyl)-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C35H48N4O6S |
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| Mol. Mass. | 652.844 |
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| SMILES | CC(C)CCN(C[C@@H](O)[C@@H]1Cc2ccc(OCCCCCC(=O)N[C@@H](C(C)C)C(=O)N1)cc2)S(=O)(=O)c1cccc2cccnc12 |
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| Structure | 
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