| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 5 |
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| Ligand | BDBM50144870 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_106668 (CHEMBL884505) |
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| EC50 | 2220±n/a nM |
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| Citation |  Wilczynski, A; Wang, XS; Joseph, CG; Xiang, Z; Bauzo, RM; Scott, JW; Sorensen, NB; Shaw, AM; Millard, WJ; Richards, NG; Haskell-Luevano, C Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands. J Med Chem47:2194-207 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 5 |
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| Name: | Melanocortin receptor 5 |
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| Synonyms: | MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36966.58 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P41149 |
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| Residue: | 325 |
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| Sequence: | MNSSSTLTVLNLTLNASEDGILGSNVKNKSLACEEMGIAVEVFLTLGLVSLLENILVIGA
IVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDS
MICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIY
YESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRTSMKGAITL
TMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQ
EMRRTFKEIVCCHGFRRPCRLLGGY
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| BDBM50144870 |
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| n/a |
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| Name | BDBM50144870 |
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| Synonyms: | CHEMBL410091 | Tyr-c[Asp-Trp-Arg-DPhe-Asn-Ala-Phe-Dpr]-Tyr-NH2 |
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| Type | Small organic molecule |
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| Emp. Form. | C68H80N18O17 |
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| Mol. Mass. | 1421.4732 |
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| SMILES | C[C@@H]1NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(=O)NC(NC(=O)C(=O)[C@@H](Cc2ccccc2)NC1=O)C(=O)NN[C@H](Cc1ccc(O)cc1)C(=O)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NN |
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| Structure | 
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