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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Peroxisome proliferator-activated receptor gamma | ||
| Ligand | BDBM50373026 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_466274 (CHEMBL950103) | ||
| EC50 | 10000±n/a nM | ||
| Citation |  Aoki, T; Asaki, T; Hamamoto, T; Sugiyama, Y; Ohmachi, S; Kuwabara, K; Murakami, K; Todo, M Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonists. Bioorg Med Chem Lett18:2128-32 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Peroxisome proliferator-activated receptor gamma | |||
| Name: | Peroxisome proliferator-activated receptor gamma | ||
| Synonyms: | NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2 | ||
| Type: | Nuclear Receptor | ||
| Mol. Mass.: | 57613.46 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P37231 | ||
| Residue: | 505 | ||
| Sequence: |
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| BDBM50373026 | |||
| n/a | |||
| Name | BDBM50373026 | ||
| Synonyms: | CHEMBL271873 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H31NO5 | ||
| Mol. Mass. | 401.4959 | ||
| SMILES | CC(C)C[C@]1(OC[C@H](CCCCc2nc(oc2C)-c2ccccc2)CO1)C(O)=O |wU:7.7,4.28,wD:4.3,(30.14,-5.75,;30.16,-4.21,;31.5,-3.45,;28.83,-3.42,;28.85,-1.88,;28.85,-.33,;27.5,.45,;26.17,-.33,;24.94,.59,;23.52,-.02,;22.29,.91,;20.87,.3,;19.63,1.22,;18.14,.8,;17.29,2.08,;18.25,3.28,;19.68,2.74,;20.99,3.57,;15.75,2.09,;14.97,.75,;13.44,.75,;12.66,2.08,;13.44,3.41,;14.97,3.41,;26.17,-1.88,;27.5,-2.65,;30.19,-1.13,;31.52,-1.91,;30.21,.41,)| | ||
| Structure | 
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