| Reaction Details |
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 | Report a problem with these data |
| Target | Endo-beta-N-acetylglucosaminidase |
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| Ligand | BDBM50373151 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_467015 (CHEMBL924919) |
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| IC50 | 220±n/a nM |
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| Citation |  Li, B; Takegawa, K; Suzuki, T; Yamamoto, K; Wang, LX Synthesis and inhibitory activity of oligosaccharide thiazolines as a class of mechanism-based inhibitors for endo-beta-N-acetylglucosaminidases. Bioorg Med Chem16:4670-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Endo-beta-N-acetylglucosaminidase |
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| Name: | Endo-beta-N-acetylglucosaminidase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 72045.14 |
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| Organism: | Arthrobacter protophormiae |
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| Description: | ChEMBL_467015 |
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| Residue: | 645 |
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| Sequence: | MRKAFLVGLVCTACVLLHDDPVAASTYNGPLSSHWFPEELAQWEPDSDPDAPFNRSHVPL
EPGRVANRVNANADKDAHLVSLSALNRHTSGVPSQGAPVFYENTFSYWHYTDLMVYWAGS
AGEGIIVPPSADVIDASHRNGVPILGNVFFPPTVYGGQLEWLEQMLEQEEDGSFPLADKL
LEVADYYGFDGWFINQETEGADEGTAEAMQAFLVYLQEQKPEGMHIMWYDSMIDTGAIAW
QNHLTDRNKMYLQNGSTRVADSMFLNFWWRDQRQSNELAQALGRSPYDLYAGVDVEARGT
STPVQWEGLFPEGEKAHTSLGLYRPDWAFQSSETMEAFYEKELQFWVGSTGNPAETDGQS
NWPGMAHWFPAKSTATSVPFVTHFNTGSGAQFSAEGKTVSEQEWNNRSLQDVLPTWRWIQ
HGGDLEATFSWEEAFEGGSSLQWHGSLAEGEHAQIELYQTELPISEGTSLTWTFKSEHGN
DLNVGFRLDGEEDFRYVEGEQRESINGWTQWTLPLDAFAGQTITGLAFAAEGNETGLAEF
YIGQLAVGADSEKPAAPNVNVRQYDPDPSGIQLVWEKQSNVHHYRVYKETKHGKELIGTS
AGDRIYLEGLVEESKQNDVRLHIEALSETFVPSDARMIDIKSGSF
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| BDBM50373151 |
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| n/a |
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| Name | BDBM50373151 |
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| Synonyms: | CHEMBL259756 |
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| Type | Small organic molecule |
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| Emp. Form. | C62H103NO49S |
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| Mol. Mass. | 1678.524 |
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| SMILES | CC1=N[C@H]2[C@@H](O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO[C@H]4O[C@H](CO[C@H]5O[C@H](CO[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H](O)[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]6O)[C@@H]5O)[C@@H]4O)[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H]3O)[C@@H]2O)S1 |t:1| |
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| Structure | 
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