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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase Lck | ||
| Ligand | BDBM50112952 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_468975 (CHEMBL952120) | ||
| IC50 | >12500±n/a nM | ||
| Citation |  Kolb, P; Huang, D; Dey, F; Caflisch, A Discovery of kinase inhibitors by high-throughput docking and scoring based on a transferable linear interaction energy model. J Med Chem51:1179-88 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase Lck | |||
| Name: | Tyrosine-protein kinase Lck | ||
| Synonyms: | 2.7.10.2 | LCK | LCK_HUMAN | LSK | Leukocyte C-terminal Src kinase | Lymphocyte cell-specific protein-tyrosine kinase | Lymphocyte-specific protein tyrosine kinase | P56-LCK | Protein YT16 | Proto-oncogene Lck | Proto-oncogene tyrosine-protein kinase LCK | Src/Lck kinase | T cell-specific protein-tyrosine kinase | ||
| Type: | n/a | ||
| Mol. Mass.: | 57987.83 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P06239 | ||
| Residue: | 509 | ||
| Sequence: |
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| BDBM50112952 | |||
| n/a | |||
| Name | BDBM50112952 | ||
| Synonyms: | 4-(2,6-Dimethyl-phenyl)-imidazo[1,5-a]quinoxaline | 4-(2,6-dimethylphenyl)imidazo[1,5-a]quinoxaline | CHEMBL30250 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H15N3 | ||
| Mol. Mass. | 273.3318 | ||
| SMILES | Cc1cccc(C)c1-c1nc2ccccc2n2cncc12 |(10.14,-7.28,;11.48,-6.52,;12.82,-7.3,;14.17,-6.53,;14.17,-4.97,;12.84,-4.19,;12.84,-2.66,;11.49,-4.97,;10.16,-4.18,;8.81,-4.95,;7.49,-4.18,;6.16,-4.95,;4.83,-4.18,;4.83,-2.64,;6.16,-1.87,;7.49,-2.64,;8.81,-1.87,;9.14,-.37,;10.67,-.22,;11.31,-1.61,;10.16,-2.64,)| | ||
| Structure | 
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