| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Galectin-3 |
|---|
| Ligand | BDBM50241034 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_510245 (CHEMBL1005623) |
|---|
| Kd | 313000±n/a nM |
|---|
| Citation |  Giguère, D; Bonin, MA; Cloutier, P; Patnam, R; St-Pierre, C; Sato, S; Roy, R Synthesis of stable and selective inhibitors of human galectins-1 and -3. Bioorg Med Chem16:7811-23 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Galectin-3 |
|---|
| Name: | Galectin-3 |
|---|
| Synonyms: | LEG3_HUMAN | LGALS3 | MAC2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 26156.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P17931 |
|---|
| Residue: | 250 |
|---|
| Sequence: | MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPP
GAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNL
PLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNN
WGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDI
DLTSASYTMI
|
|
|
|---|
| BDBM50241034 |
|---|
| n/a |
|---|
| Name | BDBM50241034 |
|---|
| Synonyms: | (2S,3R,4S,5R,6R)-2-((2R,3S,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-(naphthalen-2-ylsulfonyl)-tetrahydro-2H-pyran-3-yloxy)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol | CHEMBL203050 | beta-D-lactosyl naphthyl sulfone |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H28O12S |
|---|
| Mol. Mass. | 516.516 |
|---|
| SMILES | OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O[C@@H]2CO)S(=O)(=O)c2ccc3ccccc3c2)[C@H](O)[C@@H](O)[C@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
