| Reaction Details |
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 | Report a problem with these data |
| Target | Galanin receptor type 1 |
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| Ligand | BDBM50273352 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_561974 (CHEMBL1010037) |
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| Ki | 85±n/a nM |
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| Citation |  Bulaj, G; Green, BR; Lee, HK; Robertson, CR; White, K; Zhang, L; Sochanska, M; Flynn, SP; Scholl, EA; Pruess, TH; Smith, MD; White, HS Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities. J Med Chem51:8038-47 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Galanin receptor type 1 |
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| Name: | Galanin receptor type 1 |
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| Synonyms: | GAL1-R | GALNR | GALNR1 | GALR1 | GALR1_HUMAN | Galanin R1 | Galanin receptor 1 | Galanin receptor type 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38976.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Galanin R1 GALR1 HUMAN::P47211 |
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| Residue: | 349 |
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| Sequence: | MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLAR
SKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSML
VSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPR
ASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEA
SKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNP
IIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV
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| BDBM50273352 |
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| n/a |
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| Name | BDBM50273352 |
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| Synonyms: | (S)-1-(2-((S)-2-((S)-2-((S)-2-(2-((S)-2-((S)-2-((S)-2-((S)-2-((2S,3R)-2-((S)-3-(1H-indol-3-yl)-2-(2-(methylamino)acetamido)propanamido)-3-hydroxybutanamido)-4-methylpentanamido)-4-amino-4-oxobutanamido)-3-hydroxypropanamido)propanamido)acetamido)-3-(4-hydroxyphenyl)propanamido)-4-methylpentanamido)-4-methylpentanamido)acetyl)-N-((S)-1-((S)-1-((S)-1-amino-1-oxo-6-palmitamidohexan-2-ylamino)-1-oxopropan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide | CHEMBL526862 |
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| Type | Small organic molecule |
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| Emp. Form. | C95H150N22O21 |
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| Mol. Mass. | 1936.3423 |
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| SMILES | CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC)[C@@H](C)O)C(N)=O |r| |
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| Structure | 
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