| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1B) dopamine receptor |
|---|
| Ligand | BDBM78433 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_540495 (CHEMBL1030599) |
|---|
| Ki | 21±n/a nM |
|---|
| Citation |  von Coburg, Y; Kottke, T; Weizel, L; Ligneau, X; Stark, H Potential utility of histamine H3 receptor antagonist pharmacophore in antipsychotics. Bioorg Med Chem Lett19:538-42 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1B) dopamine receptor |
|---|
| Name: | D(1B) dopamine receptor |
|---|
| Synonyms: | D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 52943.41 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21918 |
|---|
| Residue: | 477 |
|---|
| Sequence: | MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVL
VCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFD
IMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNW
HRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAI
MIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSV
IMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYA
FNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTP
GNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
|
|
|
|---|
| BDBM78433 |
|---|
| n/a |
|---|
| Name | BDBM78433 |
|---|
| Synonyms: | 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride | 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride | 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride | FLUPHENAZINE | FLUPHENAZINE HYDROCHLORIDE | MLS001076508 | SMR000058411 | cid_3372 | cid_6602611 | med.21724, Compound 17 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H26F3N3OS |
|---|
| Mol. Mass. | 437.522 |
|---|
| SMILES | OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
