| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1b receptor |
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| Ligand | BDBM50299334 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_590267 (CHEMBL1052802) |
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| Ki | 114±n/a nM |
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| Citation |  Scott, JD; Miller, MW; Li, SW; Lin, SI; Vaccaro, HA; Hong, L; Mullins, DE; Guzzi, M; Weinstein, J; Hodgson, RA; Varty, GB; Stamford, AW; Chan, TY; McKittrick, BA; Greenlee, WJ; Priestley, T; Parker, EM Tetrahydroquinoline sulfonamides as vasopressin 1b receptor antagonists. Bioorg Med Chem Lett19:6018-22 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1b receptor |
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| Name: | Vasopressin V1b receptor |
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| Synonyms: | AVPR V1b | AVPR V3 | AVPR1B | AVPR3 | Antidiuretic hormone receptor 1b | V1BR_HUMAN | V1bR | VASOPRESSIN V1B | VPR3 | Vasopressin V1b receptor | Vasopressin V1b receptor (V1b) | Vasopressin V3 | Vasopressin V3 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 46985.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47901 |
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| Residue: | 424 |
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| Sequence: | MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
TIIF
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| BDBM50299334 |
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| n/a |
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| Name | BDBM50299334 |
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| Synonyms: | (1-(4-chlorophenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)methyl 4-(thiophen-2-ylmethylamino)piperidine-1-carboxylate | CHEMBL577816 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30ClN3O4S2 |
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| Mol. Mass. | 560.128 |
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| SMILES | Clc1ccc(cc1)S(=O)(=O)N1C(COC(=O)N2CCC(CC2)NCc2cccs2)CCc2ccccc12 |
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| Structure | 
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