| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 5A |
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| Ligand | BDBM10755 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_761948 (CHEMBL1817467) |
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| Ki | 170±n/a nM |
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| Citation |  Dolusic, E; Larrieu, P; Moineaux, L; Stroobant, V; Pilotte, L; Colau, D; Pochet, L; Van den Eynde, B; Masereel, B; Wouters, J; Frédérick, R Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators. J Med Chem54:5320-34 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 5A |
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| Name: | 5-hydroxytryptamine receptor 5A |
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| Synonyms: | 5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A |
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| Type: | Enzyme |
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| Mol. Mass.: | 40266.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47898 |
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| Residue: | 357 |
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| Sequence: | MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLL
VLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFG
WGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVS
PISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIP
FFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
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| BDBM10755 |
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| n/a |
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| Name | BDBM10755 |
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| Synonyms: | 14C-5-hydroxy tryptamine creatinine disulfate | 2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid) | 5-HT | 5-Hydroxy Tryptamine | 5-hydroxy tryptamine creatinine disulfate | CHEMBL535832 | Serotonin | [3H]-5-HT |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12N2O |
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| Mol. Mass. | 176.2151 |
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| SMILES | NCCc1c[nH]c2ccc(O)cc12 |
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| Structure | 
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