| Reaction Details |
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 | Report a problem with these data |
| Target | Inosine-5'-monophosphate dehydrogenase 2 |
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| Ligand | BDBM50356642 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_785420 (CHEMBL1919799) |
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| IC50 | >100000±n/a nM |
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| Citation |  Maruo, S; Kuriyama, I; Kuramochi, K; Tsubaki, K; Yoshida, H; Mizushina, Y Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response. Bioorg Med Chem19:5803-12 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Inosine-5'-monophosphate dehydrogenase 2 |
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| Name: | Inosine-5'-monophosphate dehydrogenase 2 |
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| Synonyms: | IMDH2_MOUSE | Impdh2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55818.95 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1297303 |
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| Residue: | 514 |
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| Sequence: | MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT
LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV
LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMT
KREDLVVAPAGVTLKEANEILQRSKKGKLPIVNENDELVAIIARTDLKKNRDYPLASKDA
KKQLLCGAAIGTHEDDKYRLDLLALAGVDVVVLDSSQGNSIFQINMIKYIKEKYPSLQVI
GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP
VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM
DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR
AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
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| BDBM50356642 |
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| n/a |
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| Name | BDBM50356642 |
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| Synonyms: | CHEMBL1917196 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28O4 |
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| Mol. Mass. | 356.4553 |
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| SMILES | CCCCCCCCCCCC(=O)Oc1cccc2C(=O)C=CC(=O)c12 |c:21| |
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| Structure | 
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