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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(2) dopamine receptor | ||
| Ligand | BDBM50382307 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_816864 (CHEMBL2026135) | ||
| Ki | 53.4±n/a nM | ||
| Citation |  Agai-Csongor, E; Domány, G; Nógrádi, K; Galambos, J; Vágó, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Sághy, K; Laszy, J; Gyertyán, I; Zájer-Balázs, M; Gémesi, L; Kapás, M; Szombathelyi, Z Discovery of cariprazine (RGH-188): a novel antipsychotic acting on dopamine D3/D2 receptors. Bioorg Med Chem Lett22:3437-40 (2012) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(2) dopamine receptor | |||
| Name: | D(2) dopamine receptor | ||
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 50931.60 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | P61169 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM50382307 | |||
| n/a | |||
| Name | BDBM50382307 | ||
| Synonyms: | CHEMBL2024523 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H33ClN4O | ||
| Mol. Mass. | 392.966 | ||
| SMILES | CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2)CC1 |r,wU:6.5,wD:9.9,(24.62,.37,;25.95,-.4,;25.95,-1.94,;27.29,.37,;27.29,1.91,;28.62,-.41,;29.95,.37,;29.95,1.91,;31.28,2.68,;32.61,1.91,;33.95,2.67,;35.28,1.9,;36.61,2.66,;37.94,1.88,;39.27,2.64,;39.28,4.18,;37.95,4.96,;36.61,4.2,;40.62,4.95,;40.63,6.48,;41.96,7.24,;43.3,6.46,;43.29,4.92,;44.62,4.14,;41.95,4.16,;32.61,.37,;31.28,-.4,)| | ||
| Structure | 
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