| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 1 |
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| Ligand | BDBM41999 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_830417 (CHEMBL2061095) |
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| Ki | 70±n/a nM |
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| Citation |  Lavecchia, A; Di Giovanni, C; Pesapane, A; Montuori, N; Ragno, P; Martucci, NM; Masullo, M; De Vendittis, E; Novellino, E Discovery of new inhibitors of Cdc25B dual specificity phosphatases by structure-based virtual screening. J Med Chem55:4142-58 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 1 |
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| Name: | M-phase inducer phosphatase 1 |
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| Synonyms: | CDC25A | Dual specificity phosphatase (Cdc25A) | Dual specificity phosphatase Cdc25A | M-phase inducer phosphatase 1 | MPIP1_HUMAN | phosphatase Cdc25 |
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| Type: | Protein |
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| Mol. Mass.: | 59090.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30304 |
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| Residue: | 524 |
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| Sequence: | MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP
ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL
WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK
ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI
SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT
DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY
CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
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| BDBM41999 |
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| n/a |
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| Name | BDBM41999 |
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| Synonyms: | 3-(3,4,5-trihydroxy-6-keto-xanthen-9-yl)propionic acid | 3-(3,4,5-trihydroxy-6-oxo-9-xanthenyl)propanoic acid | 3-(3,4,5-trihydroxy-6-oxoxanthen-9-yl)propanoic acid | 3-[3,4,5-tris(oxidanyl)-6-oxidanylidene-xanthen-9-yl]propanoic acid | MLS-0111617.0001 | cid_274127 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12O7 |
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| Mol. Mass. | 316.2623 |
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| SMILES | OC(=O)CCc1c2ccc(O)c(O)c2oc2c(O)c(=O)ccc12 |
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| Structure | 
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