| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin S |
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| Ligand | BDBM50392206 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_852706 (CHEMBL2156828) |
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| Ki | 94±n/a nM |
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| Citation |  Frizler, M; Schmitz, J; Schulz-Fincke, AC; Gütschow, M Selective nitrile inhibitors to modulate the proteolytic synergism of cathepsins S and F. J Med Chem55:5982-6 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin S |
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| Name: | Cathepsin S |
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| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
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| Type: | Protein |
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| Mol. Mass.: | 37507.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25774 |
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| Residue: | 331 |
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| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
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| BDBM50392206 |
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| n/a |
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| Name | BDBM50392206 |
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| Synonyms: | CHEMBL2153169 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21N3O4S3 |
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| Mol. Mass. | 439.572 |
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| SMILES | CC(C)CS(=O)(=O)CC(NC(=O)c1ccc(s1)-c1cccs1)C(=O)NCC#N |
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| Structure | 
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