| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Monoglyceride lipase |
|---|
| Ligand | BDBM50394373 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_854555 (CHEMBL2161050) |
|---|
| IC50 | 23±n/a nM |
|---|
| Citation |  Morera, L; Labar, G; Ortar, G; Lambert, DM Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold. Bioorg Med Chem20:6260-75 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Monoglyceride lipase |
|---|
| Name: | Monoglyceride lipase |
|---|
| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN |
|---|
| Type: | Hydrolase |
|---|
| Mol. Mass.: | 33264.56 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). |
|---|
| Residue: | 303 |
|---|
| Sequence: | MPEESSPRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEE
LARMLMGLDLLVFAHDHVGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLG
HSMGGAIAILTAAERPGHFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPID
SSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADR
LCDSKGAYLLMELAKSQDKTLKIYEGAYHVLHKELPEVTNSVFHEINMWVSQRTATAGTA
SPP
|
|
|
|---|
| BDBM50394373 |
|---|
| n/a |
|---|
| Name | BDBM50394373 |
|---|
| Synonyms: | CHEMBL2159777 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H23N5O |
|---|
| Mol. Mass. | 397.4723 |
|---|
| SMILES | O=C(N1CCN(Cc2cccc(c2)-c2ccccc2)CC1)n1nnc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
