Reaction Details |
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Target | Prostaglandin E synthase |
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Ligand | BDBM50394748 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_859393 (CHEMBL2167299) |
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IC50 | 3600±n/a nM |
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Citation | Wu, Y; He, C; Gao, Y; He, S; Liu, Y; Lai, L Dynamic modeling of human 5-lipoxygenase-inhibitor interactions helps to discover novel inhibitors. J Med Chem55:2597-605 (2012) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Prostaglandin E synthase |
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Name: | Prostaglandin E synthase |
Synonyms: | MGST1L1 | MPGES1 | PGES | PIG12 | PTGES | PTGES_HUMAN | Prostaglandin E synthase (PGES-1) | Prostaglandin E synthase 1 (mPGES-1) | Prostaglandin E synthase-1 (PGES-1) | Prostaglandin E synthase/G/H synthase 2 | Prostaglandin E2 synthase-1 ( mPGES-1) |
Type: | Protein |
Mol. Mass.: | 17112.22 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 152 |
Sequence: | MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
LRAPIRSVTYTLAQLPCASMALQILWEAARHL
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BDBM50394748 |
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n/a |
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Name | BDBM50394748 |
Synonyms: | CHEMBL2163347 |
Type | Small organic molecule |
Emp. Form. | C17H10N2O6 |
Mol. Mass. | 338.2711 |
SMILES | [O-][N+](=O)c1cc(cc(c1)[N+]([O-])=O)C(=O)Oc1cccc2ccccc12 |
Structure |
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