| Reaction Details |
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 | Report a problem with these data |
| Target | Scavenger receptor class B member 1 |
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| Ligand | BDBM50397853 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_872680 (CHEMBL2184660) |
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| IC50 | 15±n/a nM |
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| Citation |  Mittapalli, GK; Zhao, F; Jackson, A; Gao, H; Lee, H; Chow, S; Kaur, MP; Nguyen, N; Zamboni, R; McKelvy, J; Wong-Staal, F; Macdonald, JE Discovery of ITX 4520: a highly potent orally bioavailable hepatitis C virus entry inhibitor. Bioorg Med Chem Lett22:4955-61 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Scavenger receptor class B member 1 |
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| Name: | Scavenger receptor class B member 1 |
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| Synonyms: | CD36 and LIMPII analogous 1 | CD36 antigen-like 1 | CD36L1 | CD_antigen=CD36 | CLA-1 | CLA1 | Collagen type I receptor, thrombospondin receptor-like 1 | SCARB1 | SCRB1_HUMAN | SR-BI | SRB1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60889.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_872680 |
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| Residue: | 552 |
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| Sequence: | MGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKNVRIDPSSLSFNMWKEIP
IPFYLSVYFFDVMNPSEILKGEKPQVRERGPYVYREFRHKSNITFNNNDTVSFLEYRTFQ
FQPSKSHGSESDYIVMPNILVLGAAVMMENKPMTLKLIMTLAFTTLGERAFMNRTVGEIM
WGYKDPLVNLINKYFPGMFPFKDKFGLFAELNNSDSGLFTVFTGVQNISRIHLVDKWNGL
SKVDFWHSDQCNMINGTSGQMWPPFMTPESSLEFYSPEACRSMKLMYKESGVFEGIPTYR
FVAPKTLFANGSIYPPNEGFCPCLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTG
LHPNQEAHSLFLDIHPVTGIPMNCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAESG
AMEGETLHTFYTQLVLMPKVMHYAQYVLLALGCVLLLVPVICQIRSQVGAGQRAARADSH
SLACWGKGASDRTLWPTAAWSPPPAAVLRLCRSGSGHCWGLRSTLASFACRVATTLPVLE
GLGPSLGGGTGS
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| BDBM50397853 |
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| n/a |
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| Name | BDBM50397853 |
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| Synonyms: | CHEMBL2179487 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H29F2N5O2 |
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| Mol. Mass. | 481.5376 |
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| SMILES | CCc1cc(CC)nc(OCCCn2c3CCC(F)(F)Cc3c3cc(ccc23)-c2nc(C)no2)n1 |
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| Structure | 
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