| Reaction Details |
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 | Report a problem with these data |
| Target | Dopamine beta-hydroxylase |
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| Ligand | BDBM50406076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_59425 |
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| IC50 | 707946±n/a nM |
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| Citation |  Burke, BJ; Hopfinger, AJ 1-(substituted-benzyl)imidazole-2(3H)-thione inhibitors of dopamine beta-hydroxylase. J Med Chem33:274-81 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Dopamine beta-hydroxylase |
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| Name: | Dopamine beta-hydroxylase |
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| Synonyms: | DOPO_RAT | Dbh |
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| Type: | PROTEIN |
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| Mol. Mass.: | 69869.10 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_59425 |
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| Residue: | 620 |
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| Sequence: | MQPHLSHQPCWSLPSPSVREAASMYGTAVAIFLVILVAALQGSEPPESPFPYHIPLDPEG
TLELSWNVSYDQEIIHFQLQVQGPRAGVLFGMSDRGEMENADLVMLWTDGDRTYFADAWS
DQKGQIHLDTHQDYQLLQAQRVSNSLSLLFKRPFVTCDPKDYVIEDDTVHLVYGILEEPF
QSLEAINTSGLHTGLQQVQLLKPEVSTPAMPADVQTMDIRAPDVLIPSTETTYWCYITEL
PLHFPRHHIIMYEAIVTEGNEALVHHMEVFQCTNESEAFPMFNGPCDSKMKPDRLNYCRH
VLAAWALGAKAFYYPEEAGVPLGSSGSSRFLRLEVHYHNPRNIQGRRDSSGIRLHYTASL
RPNEAGIMELGLVYTPLMAIPPQETTFVLTGYCTDRCTQMALPKSGIRIFASQLHTHLTG
RKVITVLARDGQQREVVNRDNHYSPHFQEIRMLKNAVTVHQGDVLITSCTYNTENRTMAT
VGGFGILEEMCVNYVHYYPKTELELCKSAVDDGFLQKYFHIVNRFGNEEVCTCPQASVPQ
QFASVPWNSFNRDMLKALYNYAPISVHCNKTSAVRFPGNWNLQPLPNITSAVEEPDPRCP
IRQTRGPAGPFVVITHGGRH
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| BDBM50406076 |
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| n/a |
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| Name | BDBM50406076 |
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| Synonyms: | CHEMBL292989 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H8Cl2N2S |
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| Mol. Mass. | 259.155 |
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| SMILES | Clc1cccc(Cl)c1Cn1cc[nH]c1=S |
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| Structure | 
|
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