| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
|---|
| Ligand | BDBM50417063 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_665021 (CHEMBL1260131) |
|---|
| Ki | 200±n/a nM |
|---|
| Citation |  Handzlik, J; Pertz, HH; Görnemann, T; Jähnichen, S; Kiec-Kononowicz, K Search for influence of spatial properties on affinity ata1-adrenoceptor subtypes for phenylpiperazine derivatives of phenytoin. Bioorg Med Chem Lett20:6152-6 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1A adrenergic receptor |
|---|
| Name: | Alpha-1A adrenergic receptor |
|---|
| Synonyms: | ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 51620.15 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P43140 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACT
TARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
|
|
|
|---|
| BDBM50417063 |
|---|
| n/a |
|---|
| Name | BDBM50417063 |
|---|
| Synonyms: | CHEMBL503007 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H36N4O6 |
|---|
| Mol. Mass. | 572.6514 |
|---|
| SMILES | COC(=O)CN1C(=O)N(CC(O)CN2CCN(CC2)c2ccccc2OC)C(C1=O)(c1ccccc1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
