| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin S |
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| Ligand | BDBM50417994 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_719166 (CHEMBL1679625) |
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| IC50 | >25118.86±n/a nM |
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| Citation |  Lainé, D; Palovich, M; McCleland, B; Petitjean, E; Delhom, I; Xie, H; Deng, J; Lin, G; Davis, R; Jolit, A; Nevins, N; Zhao, B; Villa, J; Schneck, J; McDevitt, P; Midgett, R; Kmett, C; Umbrecht, S; Peck, B; Davis, AB; Bettoun, D Discovery of novel cyanamide-based inhibitors of cathepsin C. ACS Med Chem Lett2:142-147 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin S |
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| Name: | Cathepsin S |
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| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
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| Type: | Protein |
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| Mol. Mass.: | 37507.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25774 |
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| Residue: | 331 |
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| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
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| BDBM50417994 |
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| n/a |
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| Name | BDBM50417994 |
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| Synonyms: | CHEMBL1672431 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H19N3O4S |
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| Mol. Mass. | 325.383 |
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| SMILES | COc1ccc(OC)c(c1)S(=O)(=O)N[C@@H]1C[C@@H](C)N(C1)C#N |r| |
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| Structure | 
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