| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin S |
|---|
| Ligand | BDBM50418003 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_719166 (CHEMBL1679625) |
|---|
| IC50 | 1584.89±n/a nM |
|---|
| Citation |  Lainé, D; Palovich, M; McCleland, B; Petitjean, E; Delhom, I; Xie, H; Deng, J; Lin, G; Davis, R; Jolit, A; Nevins, N; Zhao, B; Villa, J; Schneck, J; McDevitt, P; Midgett, R; Kmett, C; Umbrecht, S; Peck, B; Davis, AB; Bettoun, D Discovery of novel cyanamide-based inhibitors of cathepsin C. ACS Med Chem Lett2:142-147 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin S |
|---|
| Name: | Cathepsin S |
|---|
| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 37507.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P25774 |
|---|
| Residue: | 331 |
|---|
| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
|
|
|
|---|
| BDBM50418003 |
|---|
| n/a |
|---|
| Name | BDBM50418003 |
|---|
| Synonyms: | CHEMBL1672419 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H16N2 |
|---|
| Mol. Mass. | 200.2795 |
|---|
| SMILES | N#CN1CCC(CCc2ccccc2)C1 |
|---|
| Structure | 
|
|---|
Search and Browse
